diff --git a/python/CMakeLists.txt b/python/CMakeLists.txt
index 38aca73dc57..e9a25f4e3fe 100644
--- a/python/CMakeLists.txt
+++ b/python/CMakeLists.txt
@@ -170,6 +170,10 @@ if(NOT WITH_GUI)
   set(SIP_DISABLE_FEATURES ${SIP_DISABLE_FEATURES} HAVE_GUI)
 endif()
 
+if(NOT WITH_QTSERIALPORT)
+  set(SIP_DISABLE_FEATURES ${SIP_DISABLE_FEATURES} HAVE_QTSERIALPORT)
+endif()
+
 configure_file(${CMAKE_CURRENT_SOURCE_DIR}/core/project.py.in ${CMAKE_CURRENT_BINARY_DIR}/core/project.py @ONLY)
 configure_file(${CMAKE_CURRENT_SOURCE_DIR}/core/pyproject.toml.in ${CMAKE_CURRENT_BINARY_DIR}/core/pyproject.toml @ONLY)
 GENERATE_SIP_PYTHON_MODULE_CODE(qgis._core core/core.sip "${sip_files_core}" cpp_files)
diff --git a/python/core/auto_generated/sensor/qgsabstractsensor.sip.in b/python/core/auto_generated/sensor/qgsabstractsensor.sip.in
index 5ed514f8d34..e75dc3ee25b 100644
--- a/python/core/auto_generated/sensor/qgsabstractsensor.sip.in
+++ b/python/core/auto_generated/sensor/qgsabstractsensor.sip.in
@@ -32,10 +32,12 @@ An abstract base class for sensor classes
       {
         sipType = sipType_QgsUdpSocketSensor;
       }
+#if defined( HAVE_QTSERIALPORT )
       else if ( item->type() == QLatin1String( "serial_port" ) && dynamic_cast<QgsSerialPortSensor *>( item ) != NULL )
       {
         sipType = sipType_QgsSerialPortSensor;
       }
+#endif
       else
       {
         sipType = sipType_QgsAbstractSensor;
diff --git a/python/core/auto_generated/sensor/qgsiodevicesensor.sip.in b/python/core/auto_generated/sensor/qgsiodevicesensor.sip.in
index b3c892fca42..3a094d3eda8 100644
--- a/python/core/auto_generated/sensor/qgsiodevicesensor.sip.in
+++ b/python/core/auto_generated/sensor/qgsiodevicesensor.sip.in
@@ -184,6 +184,7 @@ Sets the ``port`` the socket connects to.
 
 };
 
+%If (HAVE_QTSERIALPORT)
 
 class QgsSerialPortSensor : QgsIODeviceSensor
 {
@@ -239,6 +240,7 @@ Sets the serial port the sensor connects to.
 
 
 };
+%End
 
 
 
diff --git a/python/core/core.sip.in b/python/core/core.sip.in
index 250ab320fbe..a860638bf93 100644
--- a/python/core/core.sip.in
+++ b/python/core/core.sip.in
@@ -100,6 +100,7 @@ done:
 %Import QtPositioning/QtPositioningmod.sip
 
 %Feature HAVE_GUI
+%Feature HAVE_QTSERIALPORT
 %Feature ANDROID
 %Feature VECTOR_MAPPED_TYPE
 
diff --git a/src/core/sensor/qgsabstractsensor.h b/src/core/sensor/qgsabstractsensor.h
index 9474f3c88f7..a4b59743178 100644
--- a/src/core/sensor/qgsabstractsensor.h
+++ b/src/core/sensor/qgsabstractsensor.h
@@ -50,10 +50,12 @@ class CORE_EXPORT QgsAbstractSensor : public QObject
       {
         sipType = sipType_QgsUdpSocketSensor;
       }
+#if defined( HAVE_QTSERIALPORT )
       else if ( item->type() == QLatin1String( "serial_port" ) && dynamic_cast<QgsSerialPortSensor *>( item ) != NULL )
       {
         sipType = sipType_QgsSerialPortSensor;
       }
+#endif
       else
       {
         sipType = sipType_QgsAbstractSensor;
diff --git a/src/core/sensor/qgsiodevicesensor.h b/src/core/sensor/qgsiodevicesensor.h
index 690b67f2dca..68967e56d99 100644
--- a/src/core/sensor/qgsiodevicesensor.h
+++ b/src/core/sensor/qgsiodevicesensor.h
@@ -220,6 +220,7 @@ class CORE_EXPORT QgsUdpSocketSensor : public QgsIODeviceSensor
 };
 
 #if defined( HAVE_QTSERIALPORT )
+SIP_IF_FEATURE( HAVE_QTSERIALPORT )
 
 /**
  * \ingroup core
@@ -279,6 +280,7 @@ class CORE_EXPORT QgsSerialPortSensor : public QgsIODeviceSensor
     QString mPortName;
 
 };
+SIP_END
 #endif
 
 #endif //QGSIODEVICESENSOR_H