diff --git a/ms-windows/osgeo4w/package-nightly.cmd b/ms-windows/osgeo4w/package-nightly.cmd
index 6129ddf647d..7d1f28c9307 100644
--- a/ms-windows/osgeo4w/package-nightly.cmd
+++ b/ms-windows/osgeo4w/package-nightly.cmd
@@ -67,7 +67,7 @@ if not exist "%SETUPAPI_LIBRARY%" (echo SETUPAPI_LIBRARY not found & goto error)
 
 set CMAKE_OPT=^
 	-D SIP_BINARY_PATH=%O4W_ROOT%/apps/Python36/sip.exe ^
-	-D CMAKE_CXX_FLAGS_RELWITHDEBINFO="/MD /ZI /MP /Od /D NDEBUG /D QGISDEBUG" ^
+	-D CMAKE_CXX_FLAGS_RELWITHDEBINFO="/MD /ZI /MP /Od /D NDEBUG" ^
 	-D CMAKE_PDB_OUTPUT_DIRECTORY_RELWITHDEBINFO=%BUILDDIR%\apps\%PACKAGENAME%\pdb ^
 	-D SPATIALINDEX_LIBRARY=%O4W_ROOT%/lib/spatialindex_i.lib
 goto cmake
@@ -83,7 +83,7 @@ if not exist "%SETUPAPI_LIBRARY%" (echo SETUPAPI_LIBRARY not found & goto error)
 set CMAKE_OPT=^
 	-D SPATIALINDEX_LIBRARY=%O4W_ROOT%/lib/spatialindex-64.lib ^
 	-D SIP_BINARY_PATH=%O4W_ROOT%/apps/Python36/sip.exe ^
-	-D CMAKE_CXX_FLAGS_RELWITHDEBINFO="/MD /Zi /MP /Od /D NDEBUG /D QGISDEBUG" ^
+	-D CMAKE_CXX_FLAGS_RELWITHDEBINFO="/MD /Zi /MP /Od /D NDEBUG" ^
 	-D CMAKE_PDB_OUTPUT_DIRECTORY_RELWITHDEBINFO=%BUILDDIR%\apps\%PACKAGENAME%\pdb ^
 	-D SETUPAPI_LIBRARY="%SETUPAPI_LIBRARY%" ^
 	-D CMAKE_INSTALL_SYSTEM_RUNTIME_LIBS_NO_WARNINGS=TRUE